Nanoparticles

Nanoparticles are particulate dispersion with a size range of 10-1000 mm and consist of perishable materials like natural or synthetic polymer. The drugs are dissolved, dispersed & attached to the nanoparticle matrix. The nanoparticles are solid in nature & available in crystalline or amorphous form. Generally polymeric materials are used for the preparation of nanoparticles. In Nano capsule drugs are incorporated in a cavity surrounded by the polymeric membrane but in Nano sphere drug is uniformly shielded in polymer matrix system. Active targeting of the drugs at the specific site can be fulfilled by attachment of drug molecule with tissue or cell specific ligand but the passive targeting happened by the dispersion of the drugs in the polymer of Nano or Micro particle.

The key characteristics of the nanoparticles are - (1) improve the therapeutic activity and minimize adverse drug reactions associated with available drugs; (2) activate new classes of therapeutics; (3) Accelerate the re-invention of pharmaceutically ignored but biologically active new molecular substances that were previously underestimated. They are used in targeted drug delivery system to enhance the solubility of poorly soluble drug and also help in gene drug delivery.

  • Carbon Nanotubes
  • Dedrimers & Nano crystals
  • Gold Nano particles
  • Nano capsule & shell
  • Quantum dots
  • Nano pores, wires & cantilever
  • Polymer Nanoparticles

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