R N Saha
BITS Pilani, Dubai Campus, UAE
Title: Nanoparticulate drug delivery systems for modifi ed tissue distribution and better cancer chemotherapy
Biography
Biography: R N Saha
Abstract
New insight of diseases and pharmacokinetic information have made drug deliver totally different. It is no more just delivery of drugs, as objectives are totally different. Present approaches of design of delivery systems are more challenging and expectations are much higher. Non-selective distribution of drugs from conventional deliver systems makes dose requirement high and lead to severe side effects or toxic effects, especially in cancer chemotherapy and CNS treatment. Application of nanotechnology in drug delivery, can make modified/selective distribution, decreased dose, lesser or no side effects and better therapy. Recent studies indicated selective or modified distribution, enhanced pharmacokinetic properties and better therapeutic efficacy for nanoparticulate delivery systems of selected anticancer drugs. In vivo study of liver carcinoma therapy in animal indicated highly encouraging effi cacy with enhanced overall survival when treated with nanoparticulate systems
