Ali Awad Hamoud Al-jeboory
Uruk University, Iraq
Title: Haloxylon as an alternative nanoscience medicine in treatment of cancer
Biography
Biography: Ali Awad Hamoud Al-jeboory
Abstract
Cancer is a disease that affects about millions of Iraqi people in all age groups and both sexes. Most of current chemotherapeutic agents on the market are low index and lack of specificity with unwanted effects and cause significant damage to non-cancer tissues. Additionally, they are expensive. In Iraq, the cancer level increased because of war using dirty weapons and low care of health and poor nutrition so pushed us to look for a new drug resources, cheap and easy to get from natural medicine. However we have looked to traditional medicine which has less resistance and effective in treatment of cancer with fewer side effects. Among screening of many traditional plants we found that some of these medicinal plant of a good efficient and significant value in treatment of cancer especially after extraction of active constituent from their leaves, fruits, stems and roots. Among these are Haloxylon, Loranthus ferrugineus and Loranthus europaeus. In addition, using gold which one of inert materials. The activity of these natural materials when mixed with vincristine has shown tremendous result. This potentiation lead to decrease the dose and decrease the side effect of vincristine the structure and tunable surface functionality of these agents allows for the encapsulation of multiple entities may render them ideal drug deliver agents for various anticancer drugs which have ability to arrange excretion mode from body as a function of nanoscale diameter. From these result especially with Haloxylon active constituent may act as a new anticancer drug delivery or a new anticancer drug with high significant activity even with very low doses with low price and available resources from Iraqi desert, thus, this multifunctional unique small nanoparticulate has the potential to detect diseases, deliver medications which could change current scenario of cancer research and could be help in diagnosis at the same time. The extraction of active constituent materials includes alkaloid, flavonoids and terpenoid by using chromatography method (using a thimble of Soxhlet) with different organic solvents. The alkaloid kills the cancer cells and flavonoids with terpenoids act as antioxidant which potential the anticancer activity of these natural agents.
