Kármen Szabó
University of Debrecen, Debrecen, Hungary
Biography
Kármen Szabó is a doctoral candidate at the Inorganic and Analytical Chemistry Department of the University of Debrecen (Debrecen, Hungary). She is a member of a biochemical research group, which primarily focuses on the investigation and inhibition of carbohydrate-active enzymes (glycoenzymes). Kármen has dealt with the examination of natural and synthetic compounds that could be applied as medicaments for the treatment and/or the prevention of type 2 diabetes mellitus and its complications. She has recently been concerned with the identification and interpretation of drug promiscuity, especially for known and potential anti-diabetic agents. Drug promiscuity, which can be defined as the outstanding inhibitory effect of a compound on various unrelated target enzymes, can lead to financial losses for pharmaceutical industry if it is recognized too late. Therefore, her work can be feasible for eliminating these promiscuous inhibitors even at an early stage in drug development.
Abstract
Abstract : Study on the promiscuous nature and aggregation-tendency of 4- thiazolidinone derivatives